Inositol Hexaniacinate Review

Inositol hexaniacinate is one of the two forms of Inositol.

The second most common is hexanicotinate.

They have similar and different functions.

History & Benefits :

This substance was known since long time ago.

In 1940, nutritional science classified it as an essential nutrient.

This sugar-like substance became one of the water-soluble B vitamins.

 It can be found in the human body and vegetables. In human body, you will retrieve it in heart muscle, skeletal system, kidney and liver . In vegetables, it is present in the seeds and leaves of many plants like nuts, grains and beans.

  Inositol Hexaniacinate Dosage: 

• Dosage range: 10 to 3000 mg daily. A good advice: if you plan to use dosage greater than 2000 mg, it’s best to use it under medical supervision  
• Most common dosage: 50 mg daily  
• Dosage forms: effervescent tablets, tablets, liposomal spray, liquids. 

Indications of  inositol hexaniacinate:

It functions like niacin in the body. For this reason it has been used to support circulatory health.

It lowers elevated LDL ( Bad ) Cholesterol and simultaneously raises the level of HDL (Good) cholesterol. What make niacin hexaniacinate so popular is the fact that these functions has not been associated with the usual side effects of other supplements.

People with diabetes will have many benefits if they use it. It helps treat many complications associated with diabetes. By example, when use with chromium, this supplement helps regulate the blood sugar level.

This supplement has also been considered in the treatment of two important circulatory disorder: intermittent claudication and Raynaud’s disease. Its use in patients with Raynaud’s disease reduces the peripheral vasospasm, the main cause of the disease.

General Precautions:

It is important to inform your doctor about any dietary supplement you are taking, particularly if you are sick an under medical prescription. This will help to avoid interactions or side effects.

This supplement is considered safe until now. No side effects have been related with its use.

It’s important to remember that niacin can cause “niacin flush” with  flushing of the skin and tingling sensation. That’s the reason people prefers hexaniacinate : they can have all the benefits of niacin without its side effects.

Pregnancy/Breast-feeding precaution:

To date any adverse effects has been reported related to fetal development during pregnancy or to infants who are breast-fed.

Health Conditions Related:

Raynaud’s disease

Intermittent claudication

Drugs/Herbs Nutrient depletion:

Antibiotics : decrease the beneficial bacteria in the digestive tract. The result may be a decrease in the production of b vitamins in the body and the need of supplementation.

Estrogen-containing medications: cause a low levels of niacin in the body. In these cases, supplementation with niacin multivitamin may be necessary.

Isoniazid: decreases the level of niacin in the body. People who are taking isoniazid may need an increase supplementation of this nutrient.

Anticonvulsivants : it increases the risk of overdose and toxicity by inhibiting the breakdown of primidone and carbamazepine (anticonvulsivants ) in the body.An alteration of these medications and the dose need for treatment may result with the use of inositol hexaniacinate .